The rate of developing esophageal squamous cell carcinoma (ESCC) nearly doubles in those who both smoke and drink compared to those who only smoke or drink, according to new research published in The American Journal of Gastroenterology.
http://www.endonurse.com/news/2014/04/combination-of-alcohol-and-tobacco-increases-risk.aspx
Combination of Alcohol and Tobacco Increases Risk of Esophageal Cancer