Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive. What has puzzled researchers was how genes in the healthy cells lining the esophagus turned the normal cells into malignant ones. Now, researchers from Case Western Reserve University School of Medicine have characterized structurally abnormal genes in esophageal adenocarcinoma, the findings of which could pave way for developing new biomarkers in this fatal disease. The National Cancer Institute estimates that nearly 37,000 people are living with esophageal cancer in the United States and nearly $1.6 billion is spent on related care each year.
http://medicalxpress.com/news/2016-08-fused-genes-esophageal-cancer-cells.html
Fused genes found in esophageal cancer cells offer new clues on disease mechanisms