Preoperative chemoradiotherapy doubled median overall survival among patients with esophageal or esophagogastric junction cancer compared to surgery alone, according to the results of a phase 3 study published in the New England Journal of Medicine.
http://www.nmcancercenter.org/2012/09/10/preoperative-chemoradiotherapy-improves-survival-in-esophageal-cancer/
Preoperative Chemoradiotherapy Improves Survival in Esophageal Cancer