Proton Pump Inhibitors (PPIs) for treatment of heartburn are some of the most commonly prescribed medications, and in some countries (U.S. for example) are available as over-the-counter treatments. Common brands include Nexium, Losec, and Pariet. They have become extremely popular because they work very effectively to reduce heartburn symptoms, and until recently had been thought to be very safe for long-term use
http://www.ngnews.ca/Community/2016-03-22/article-4474600/Some-heartburn-remedies-carry-risks/1
Some heartburn remedies carry risks