Esophageal cancer is the sixth most common cause of cancer deaths worldwide. Despite the rates of some cancers falling over the past 25 years, the frequency of some esophageal cancers is growing and physicians are unable to explain why.
http://www.uofmhealth.org/news/archive/201705/u-m-faculty-identifies-clustering-esophageal-cancer
U of M Faculty Identifies Clustering of Esophageal Cancer Mortality in the Great Lakes States and New England