Extrachromosomal DNA is common in human cancer and drives poor patient outcomes
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The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including Professors Vineet Bafna and Dr.Paul Mischel of the University of California San Diego and Professor Roel Verhaak of Jackson Laboratories.
https://medicalxpress.com/news/2020-08-extrachromosomal-dna-common-human-cancer.html