This research was done in order to comprehensively evaluate the relationship between the low IGFBP–3 level and the risk, overall survival and clinical pathological characteristics of esophageal cancer. The meta–analysis recommends that for esophageal cancer, the low IGFBP–3 level is connected with high cancer risk, poor prognosis, and unfavorable tumor stage and metastasis.
http://mdlinx.pdr.net/family-medicine/news-article.cfm/6983570/0/esophageal-cancer-overall-survival-clinical-pathological/next/128/?source=scroller
The low IGFBP-3 level is associated with esophageal cancer patients: A meta-analysis Full Text