People with gastroesophageal reflux disease (GERD), a digestive problem marked by excess backflow of stomach contents, know that the resulting heartburn or regurgitation can be painful — and, in some chronic cases, damaging to one’s esophagus.
https://knowridge.com/2017/02/is-it-safe-to-take-ppis-a-gastroenterologist-explains-the-risks/
Is it safe to take PPIs? A gastroenterologist explains the risks