Chemoradiation before surgery has been shown to improve survival in patients with advanced cancers of the upper gastrointestinal tract over surgery alone, but the optimal chemotherapy for this population is unknown.
http://www.gastroendonews.com/In-the-News/Article/04-17/PET-Scans-Help-Tailor-Chemo-for-Esophageal-Cancer/40856
PET Scans Help Tailor Chemo for Esophageal Cancer